UK Research & Innovation: UKRI-1161 Laser Micro-dissection Inverted Imaging System

UK-Swindon: Laboratory, optical and precision equipments (excl. glasses).

Section I: Contracting Authority

   I.1) Name, Addresses and Contact Point(s):
       UK Research & Innovation
       Polaris House, North Star Avenue, Swindon, SN2 1FL, United Kingdom
       Tel. +44 1793867000, Email: MRCprocurement@ukri.org
       Main Address: www.ukri.org
       NUTS Code: UK

   I.2) Joint procurement:
      The contract involves joint procurement: No          
      In the case of joint procurement involving different countries, state applicable national procurement law: Not Provided
      The contract is awarded by a central purchasing body: No

   I.4)Type of the contracting authority:
      Body governed by public law

   I.5) Main activity:
      Other activity: Scientific Research

Section II: Object Of The Contract

   II.1) Scope of the procurement

      II.1.1) Title: UKRI-1161 Laser Micro-dissection Inverted Imaging System            
      Reference number: UKRI-1161

      II.1.2) Main CPV code:
         38000000 - Laboratory, optical and precision equipments (excl. glasses).
            LA21-3 - For laboratory use


      II.1.3) Type of contract: SUPPLIES

      II.1.4) Short description: Supply of MMI Laser Microdissection Inverted Imaging System with the ability to measure the presence of the oligonucleotide-based drugs (i.e. antisense and siRNA) within the tissue and assess drug action through measurement of changes in the mRNA and protein levels of the drug target. We require a brightfield/fluorescence microscope that can be employed to view, record and quantify tissues stained by H&E, in situ hybrisation (ISH) and immunohistochemistry (IHC). We also require an attached laser that can be employed to provide tissue section down to the single cell level for the analysis of drug, mRNA and protein levels. In addition, we require a system that can be expanded in the future through the addition of a confocal microscope.

      II.1.6) Information about lots
         This contract is divided into lots: No
            
      II.1.7) Total value of the procurement (excluding VAT)
          Value: 228,115.15
                  
         Currency:GBP            

   II.2) Description

      II.2.2) Additional CPV code(s):
      Not Provided

      II.2.3) Place of performance
      Nuts code:
      UK - UNITED KINGDOM
   
      Main site or place of performance:
      UNITED KINGDOM
             

      II.2.4) Description of the procurement: Supply of MMI Laser Microdissection Inverted Imaging System with the ability to measure the presence of the oligonucleotide-based drugs (i.e. antisense and siRNA) within the tissue and assess drug action through measurement of changes in the mRNA and protein levels of the drug target. We require a brightfield/fluorescence microscope that can be employed to view, record and quantify tissues stained by H&E, in situ hybrisation (ISH) and immunohistochemistry (IHC). We also require an attached laser that can be employed to provide tissue section down to the single cell level for the analysis of drug, mRNA and protein levels. In addition, we require a system that can be expanded in the future through the addition of a confocal microscope.

      II.2.5) Award criteria:
                  
      Price - Weighting: 10
            

      II.2.11) Information about options
         Options: No
         

      II.2.13) Information about European Union funds
         The procurement is related to a project and/or programme financed by European Union funds: No
         

      II.2.14) Additional information: Not Provided


Section IV: Procedure

IV.1) Description

   IV.1.1)Type of procedure: Award of a contract without prior publication of a call for competition in the Official Journal of the European Union in the cases listed below (please complete Annex D1)


   IV.1.3) Information about a framework agreement or a dynamic purchasing system
      The procurement involves the establishment of a framework agreement: No       
      

   IV.1.6) Information about electronic auction
      An electronic auction has been used: No

   IV.1.8) Information about the Government Procurement Agreement (GPA)
      The procurement is covered by the Government Procurement Agreement: No

IV.2) Administrative information

   IV.2.1) Previous publication concerning this procedure
       Not Provided
   

   IV.2.9) Information about termination of call for competition in the form of a prior information notice
      The contracting authority will not award any further contracts based on the above prior information notice: No

Section V: Award of contract

Award Of Contract (No.1)

   Contract No: UKRI-1161    
   Lot Number: Not Provided    
   Title: Not Provided

   A contract/lot is awarded: Yes


   V.2) Award of contract

      V.2.1) Date of conclusion of the contract: 25/01/2021

      V.2.2) Information about tenders
         Number of tenders received: 1
         Number of tenders received from SMEs: Not Provided          
         Number of tenders received from tenderers from other EU Member States: Not Provided          
         Number of tenders received from tenderers from non-EU Member States: Not Provided          
         Number of tenders received by electronic means: Not Provided

      V.2.3) Name and address of the contractor

      The contract has been awarded to a group of economic operators: No
         
         Contractor (No.1)
             Olympus (Uk) Ltd, N/A
             KeyMed House, Stock Road, Southend-on-Sea, Essex, SS2 5QH, United Kingdom
             Tel. +44 1702616333, Email: tom.skelhon@olympus-europa.com
             NUTS Code: UK
            The contractor is an SME: No

      V.2.4) Information on value of the contract/lot (excluding VAT)
         Initial estimated total value of the contract/lot: 225,905          
         Total value of the contract/lot: 228,115.15
         Currency: GBP

      V.2.5) Information about subcontracting
         The contract is likely to be subcontracted: No
         
Section VI: Complementary information

   VI.3) Additional information: To view this notice, please click here:
https://www.delta-esourcing.com/delta/viewNotice.html?noticeId=569061891

   VI.4) Procedures for review

      VI.4.1) Review body
          UK Research & Innovation
          Polaris House, North Star Avenue, Swindon, SN2 1FL, United Kingdom
          Tel. +44 1793867000, Email: MRCProcurement@ukri.org
          Internet address: www.ukri.org

      VI.4.3) Review procedure
         Precise information on deadline(s) for review procedures: Not Provided

      VI.4.4) Service from which information about the review procedure may be obtained
         Not Provided

   VI.5) Date of dispatch of this notice: 20/02/2021




ANNEX D

   1. Justification for the choice of the negotiated procedure without prior publication of a call for competition in accordance with Article 32 of Directive 2014/24/EU

      No tenders or no suitable tenders/requests to participate in response to: Not Provided

      The products involved are manufactured purely for the purpose of research, experiment, study or development under the conditions stated in the directive (for supplies only): No       
      
      The works, supplies or services can be provided only by a particular economic operator for the following reason: absence of competition for technical reasons

      Extreme urgency brought about by events unforeseeable for the contracting authority and in accordance with the strict conditions stated in the directive: No

      Additional deliveries by the original supplier ordered under the strict conditions stated in the directive: No

      
      
      Procurement of supplies quoted and purchased on a commodity market: No

      Purchase of supplies or services on particularly advantageous terms: No


   3. Explanation
          This system was chosen as it needed to integrate into current systems and equipment on site and was therefore the only option.

Only the Olympus MMI Laser Microdissection Inverted Imaging System has a modular system which allows the addition, integration and onboarding of these facilities such as confocal microscopy, live cell imaging and high content screening to provide a system that can deliver all of the following functions: live cell imaging, spinning disc confocal and high content screening, whilst retaining the original functionality of the system and without hardware replacement.

Also, we require a laser to micro-dissect single cells and tissue biopsies for quantifiable analysis such as RT-PCR, sequencing and western blotting. The sample capture procedure must be an upward capture system in order to reduce contamination of samples to a minimum. It must be possible to maintain an RNA-ase and DNA-ase free environment.

This is the only equipment able to deliver all the above as an integrated system.